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Type of Document	Dissertation
Author	Schmidt, Donald Emil
URN	etd-10042002-125501
Persistent URL	http://resolver.caltech.edu/CaltechETD:etd-10042002-125501
Title	Part I. Alpha-secondary isotope effects on the reaction catalyzed by fumarase; Part II. Salt effects on fumarase
Degree	PhD
Option	Chemistry
Advisory Committee	Advisor Name Title Unknown Committee Member
Keywords	none
Date of Defense	1967-03-21
Availability	unrestricted
Abstract NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document. PART I The [alpha]-secondary isotope effect of L-malic-2-T-1, 4-C[superscript 14] acid on the reaction catalyzed by fumarase was determined. Evidence was presented which indicated that the reaction proceeded by formation of a carbonium ion in a rate-determining state at C-2 which possesses little sp[superscript 2] character. PART II The effects of sodium bromide and sodium phosphate at pH 7.3 and 27[degrees] were determined. A partial kinetic and mechanistic scheme has been developed to explain these effects.
Files	Filename       Size       Approximate Download Time (Hours:Minutes:Seconds)     28.8 Modem   56K Modem   ISDN (64 Kb)   ISDN (128 Kb)   Higher-speed Access    Schmidt,jr_de_1967.pdf 5.79 Mb 00:26:47 00:13:46 00:12:03 00:06:01 00:00:30